SKU:67647856719
Thiostrepton
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Ships within 48 hours · Estimated delivery Sep 14 - Sep 19
Description
ThiostreptonThiostrepton is a cyclic peptide antibiotic isolated from Streptomyces azureus. It targets a wide variety of gram negative and gram positive bacteria, especially those causing skin infections. It has been used as a marker for selection of recombinant Streptomyces cultures. Additionally, thiostrepton has been shown to inhibit FOXM1, a gene commonly overexpressed in cancer cell lines, thus inhibiting cancer cell growth. Thiostrepton functions by binding
Because of its potency and cytotoxic nature
238 g of IPTG
Because it targets a fundamental component of cell division
a sterile filter
CHE-Gal may serve as a substrate to monitor enzymatic hydrolysis
Redox-Active Compound: Exhibits redox-dependent behavior that can influence cellular stress responses
or sensitivity/resistance in cancer cell lines
histone acetylation
Control of Gram-Negative Contaminants in Tissue Culture
In in vitro and in vivo research
Cell cycle / mitotic arrest studiesUse vincristine to synchronize cells in M phase or to probe mitotic checkpoint signaling
PubChem Chemical ID: 9257
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